Every woman wants to get rid of dark spots, acne marks, or age spots to display a bright and even complexion. However, fading hyperpigmentation can be a difficult, tedious, and slow task.
Thankfully, now there is a new product in the market that is about to revolutionize hyperpigmentation treatment and prevention (more on that later).
Indeed, Brighlette™ marine ingredient G is the result of extensive research on the melanogenesis process, down to a molecular level. It is a biotechnological extract with excellent performance and an eco-friendly profile.
But before showing you how Brighlette™ can correct melanogenesis, you must understand the skin pigmentation process.
Melanin is the pigment responsible for our skin tone and protects us from UV radiation. It is essential in photoprotection as it absorbs and scatters UV rays, acting as a sun filter.
The problem with melanin is that its deposition changes with age. Abnormalities in skin pigmentation can happen when there is overproduction and accumulation of melanin.
Then come the solar lentigines, melasma, or the dreaded age spots, leading to hyperpigmentation and uneven skin complexion. But how is melanin produced in the first place?
Melanin synthesis and deposition is a complex multi-step process controlled by the so-called melanin epidermal unit.
This pigmentation complex comprises 30 to 40 keratinocytes (skin cells) and one melanocyte (highly specialized melanin-producing cell).
Usually, UV radiation, pollution, hormone disorders, or inflammation trigger keratinocytes, thus producing stimulating factors (messengers) that subsequently activate melanocytes.
These extracellular molecules induce signaling pathways, leading to the activation and expression of melanogenic genes within the melanocyte's nucleus.
Then, as a response, these cells produce melanin contained in little cell organs or vesicles called melanosomes.
Also, in the biosynthesis of melanin, several enzymes are involved, such as tyrosinase (TYR) responsible for brown-black melanin production. This is a key enzyme in melanin production as it catalyzes the rate-limiting step.
Finally, melanin in the mature melanosomes is transported from the melanocytes to the keratinocytes on the skin surface, causing skin pigmentation.
There is extensive research on numerous compounds derived from marine organisms that work as tyrosinase inhibitors and regulate several steps of melanogenesis.
Brighlette™ Marine Ingredient G is a marine extract obtained by biotechnology from a marine microorganism (plankton species) originally from the southwest coast of Tenerife Island in Spain.
Since it is obtained through bio-based technologies, it shows an excellent sustainability profile with no harvesting or extracting from nature involved.
Indeed, Brighlette™ marine ingredient G is a great representative of Lipotec's new BIOINTEC™ blue biotechnology line, combining efficacy and an eco-friendly profile.
According to INCI nomenclature, this preservative-free transparent solution contains Glycerin, Water, Plankton Extract (0,11%), Hydrolyzed Yeast Extract, and Glycolipids.
Brighlette™ marine ingredient G consistently reduces the deposition of melanin in the epidermis. It acts on multiple steps of the melanogenic process, from melanosome formation to post-transfer pigment processing.
By understanding the melanogenic pathway and modulating the underlying mechanisms, Brighlette™ marine ingredient G can help depigment the desired areas. Thus, it effectively reduces hyperpigmented spots and brightens skin complexion.
Brighlette™ marine ingredient G reduces the presence of special receptors in the melanocyte's surface, inhibiting the expression of multiple melanogenic genes, such as MITF.
Therefore, Brighlette™ marine ingredient G can effectively downregulate the expression of proteins needed for melanosomes formation and maturation, such as melan-A, and enzymes in charge of melanin production.
In vitro assays show that Brighlette™ marine ingredient G reduces tyrosinase to 48,9% after 13 days of incubation of skin cells.
Also, it can decrease tyrosinase activity and related melanin-synthesizing enzymes by 36,3%. This reduces melanin synthesis (61,3%) and ultimate uptake or internalization of the pigment by skin cells.
Indeed, several clinical studies show the benefits of yeast extract, another ingredient of Brighlette™ marine ingredient G, as a potent melanin production inhibitor with a hypomelanogenic effect.
So, Brighlette™ marine ingredient G not only reduces melanosome formation, but they end up containing less melanin! Also, Brighlette™ marine ingredient G reduces the final step when the melanosomes are transferred to the keratinocytes.
In addition, Brighlette™ marine ingredient G stimulates the expression of DNA-repairing genes to fix possible UV-induced DNA damage (due to the loss of the protective melanin) that may lead to pigmentation changes and premature age spots.
Thus, Brighlette™ marine ingredient G shows a true brightening effect leading to a perfect and even skin tone and complexion. It both treats and prevents hyperpigmentation.
In a clinical trial, Brighlette™ marine ingredient G 2% cream was applied for eight weeks in 22 Asian volunteers between 38-53 years old with face hyperpigmentation, showing a decrease in dark spots contrast of 12,7% and increased luminance of 2,5%.
Also, Brighlette™ marine ingredient G reduced dark spots area by 6,9% and diminished melanin content by up to 61,1%, making hyperpigmentations less noticeable.
Brighlette™ marine ingredient G effectively reduces melanin content and deposition by acting on the multiple stages of the melanogenesis process.
It is an effective skin-brightening active with a completely safe profile.
Brighlette™ marine ingredient G:
Gives you a more even skin tone
Prevents dark spots or hyper-pigmented areas, which are often an early sign of aging, especially in Asian women
Lightens the complexion
Despite its many benefits, Brighlette™ marine ingredient G must be used as its manufacturer suggests, and you must not directly apply it to your skin.
So, this product should be added to a formulation at the recommended usage rate of 2%. Also, it works best within a pH range of 4.0-7.0.
Brighlette™ marine ingredient G is the perfect answer to correct melanogenesis. It literally works step by step, and little by little, to even your skin tone!